Keloid
Conditions
Interventions
Single Radiation Fraction,sRF:Patient undergoes postoperative radiotherapy within 24 hours after surgical removal of keloids: 6MeV electron beam radiotherapy, dose 13Gy, frequency 1 time
Interrupted Radiation Fraction,iRF:Patient undergoes postoperative radiotherapy within 24 hours after surgical removal of keloids: 6MeV electron beam radiation therapy, dose 9Gy, frequency 2, interval
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
13 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1 Age 13-60 years old 2 Diagnosed as keloid by at least 3 physicians 3 Keloid lesions are located in the trunk (chest, shoulders, and back) 4 Skin Fitzpatrick Type III/IV 5 No other invasive treatments such as glucocorticoid injection or laser therapy have been performed in the past 6 months
Exclusion criteria
Exclusion criteria: 1 Suffering from serious skin diseases such as psoriasis, scleroderma, etc. 2 Endocrine diseases such as diabetes, systemic lupus erythematosus and systemic sclerosis 3 Patients with systemic diseases with obvious or unstable clinical manifestations should be excluded based on the possibility of interfering with the research results, including malignant tumors, uncontrollable diabetes, uncontrollable hypertension, unstable pneumonia, organic diseases of kidney or liver, unstable myocardial ischemic diseases, dilated myocardial diseases, abnormal myocardial conduction diseases or unstable cardiovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of keloids ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical incision healing ;tumorigenesis in surgical site; | — |
Countries
China
Contacts
Public ContactXiaoLi Wu
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed