Disorders of consciousness
Conditions
Interventions
Observation group:Conventional treatment + acupuncture intervention
Waiting group:Conventional treatment
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?Patients who met the above diagnostic criteria for pDOC were included only in the VS/UWS and MCS stages; ?Those who have a first sudden onset of impaired consciousness with a clear etiology and a complete case history; ?Those without significant hydrocephalus and without severe cerebral atrophy; ?Those who have not used any sedative or antiepileptic drugs in the last 1 week; ?Age is between 18-80 years old and gender is not limited; ?Those without significant pre-morbid cognitive impairment, hearing impairment or visual impairment; ?Those who were able to communicate accurately in Chinese prior to the onset of the disease and had no significant neurologic or psychiatric history; ?Those with stable medical conditions, relatively stable vital signs, and not enrolled in another study within the last 3 months; ?Informed consent was obtained from the subject's legal representative, and the subject's legal representative voluntarily cooperated and signed the informed consent form. Note: Inclusion is only possible if the above criteria are also met.
Exclusion criteria
Exclusion criteria: ?Those who are younger than 18 years of age or older than 80 years of age; ?Combined intracranial tumors, severe hydrocephalus, those with episodes of intracranial infections or brain death, and those with other space-occupying diseases that significantly affect the study results; ?Those with a history of neurologic or psychiatric disorders or drug abuse prior to brain injury; ?Those who are unstable, whose vital signs are not stable, and who have serious complications in the respiratory and circulatory systems that are not effectively controlled; ?Those who are in the acute phase after the onset of the disease, who have been unconscious for less than 28 days or who have incomplete case information; ?Those with severe endocrine-metabolic disorders or with persistent status epilepticus; ?Pregnancy, combined multiple trauma, limb fractures, or large skin defects; ?Participants in other studies within the last 3 months; ?Subjects whose legal representatives do not agree and are unwilling to cooperate in signing the informed consent form; Note: Where any 1 of the above is met, it is excluded.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Coma Scale;Full Outline of Unresponsiveness;Nociception Coma Scale-Revised;Disability Rating Scale;Arousal rate;Efficient;Brainstem Auditory Evoked Potential;Somatosensory Evoked Potential;Mismatch Negativity;P300;Glasgow Outcome Scale-Extended; | — |
Primary
| Measure | Time frame |
|---|---|
| The Coma Recovery Scale–Revised; | — |
Countries
China
Contacts
Public ContactLiu Yiwei
West China Hospital of Sichuan University
Outcome results
None listed