Comparison of the effect of intrathecal dexmedetomidine with intravenous pumping on subarachnoid blockade

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076170

Enrollment

Unknown

Registered

2023-09-26

Start date

2022-11-22

Completion date

Unknown

Last updated

2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Group A:Intrathecal dexmedetomidine

Group B:Intravenous pumping of dexmedetomidine

Group C:Intravenous pumping of saline

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients aged 20-75 years with ASA class I-II knee arthroscopy

Exclusion criteria

Exclusion criteria: Patients with contraindications to subarachnoid block, history of allergy to local anesthetics or dextromethorphan, chronic analgesic use, atrioventricular block or unstable cardiovascular disease, block failure or need for induction of general anesthesia were excluded from the study.

Design outcomes

Primary

Measure	Time frame
Total analgesic time;Total time of sensory block;Total time of motor block;	—

Secondary

Measure	Time frame
Incidence of bradycardia;Incidence of hypotension;Ramsay sedation score;	—

Countries

China

Contacts

Public ContactQuanyi Zhang

Binzhou Medical University Hospical

3201981410@qq.com+86 189 5434 6736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026