lumbar degenerative disease
Conditions
Interventions
bupivacaine liposome :bupivacaine liposome applied in ultrasound-guided erector spinae plane block
bupivacaine hydrochloride :bupivacaine hydrochloride applied in ultrasound-guided erector spinae plane block
Sponsors
The Seventh Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 74 adult patients with ASA grade I-III who underwent elective posterior lumbar surgery, aged over 18 years old;
Exclusion criteria
Exclusion criteria: 1. Allergies to bupivacaine and bupivacaine liposomes 2. Concomitant severe underlying diseases (ASA> Grade IV) 3.Infection at the puncture site or corresponding contraindications for anesthesia, such as oral anticoagulants,coagulation related blood system diseases, nerve defects at the nerve block site, and abnormal coagulation function PLT<50 4.Severe systemic chronic disease, uncontrolled and severe liver dysfunction (Child Pugh C grade); Severe renal dysfunction (receiving dialysis treatment before surgery) 5.Patients with severe electrolyte disorders and moderate to severe anemia (Hb<90 g/L) 6.Pregnant and lactating women 7.Patients who have participated in other clinical drug trials in the past 3 months 8.Drug Addicts 9. Patient cannot cooperate 10. Previous history of lumbar spine surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative analgesic consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale Score;adverse event;Hospitalization days; | — |
Countries
China
Contacts
Public ContactWei Fuxin
The Seventh Affiliated Hospital , Sun Yat-sen University, China
Outcome results
None listed