liver failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) In line with the 2018 edition of the indications of Artificial Liver Treatment: ? Before, early and middle stages of liver failure, PTA is between 20% to 40%; patients with advanced liver failure can also be treated.? Patients waiting for liver origin before liver transplantation, rejection reaction after liver transplantation before end-stage liver disease.? Severe cholestatic liver disease with poor medical treatment; severe hyperbilirubinemia resulting from various causes. 2) Patients with the first DPMAS of liver failure; 3) Voluntary signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Participants shall participate in other clinical trials; 2) The subject or the family members did not agree to participate in the trial; 3) After the second DPMAS for the same patient; 4) The expected hospital stay in the ICU is less than 24 hours; 5) Pregnant or lactating women; 6) Age is <18 years old; 7) Patients with severe active bleeding or active blood vessels complicated by diffuse intravascular coagulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| metabonomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory indicators;Liver function indicators; | — |
Countries
China
Contacts
the Second Affiliated Hospital of Harbin Medical University