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Efficacy and safety correlation analysis of DPMAS in ICU liver failure

Efficacy and safety correlation analysis of DPMAS in ICU liver failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076156
Enrollment
Unknown
Registered
2023-09-26
Start date
2023-10-01
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver failure

Interventions

Case series:None

Sponsors

the Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) In line with the 2018 edition of the indications of Artificial Liver Treatment: ? Before, early and middle stages of liver failure, PTA is between 20% to 40%; patients with advanced liver failure can also be treated.? Patients waiting for liver origin before liver transplantation, rejection reaction after liver transplantation before end-stage liver disease.? Severe cholestatic liver disease with poor medical treatment; severe hyperbilirubinemia resulting from various causes. 2) Patients with the first DPMAS of liver failure; 3) Voluntary signing of the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Participants shall participate in other clinical trials; 2) The subject or the family members did not agree to participate in the trial; 3) After the second DPMAS for the same patient; 4) The expected hospital stay in the ICU is less than 24 hours; 5) Pregnant or lactating women; 6) Age is <18 years old; 7) Patients with severe active bleeding or active blood vessels complicated by diffuse intravascular coagulation.

Design outcomes

Primary

MeasureTime frame
metabonomics;

Secondary

MeasureTime frame
Inflammatory indicators;Liver function indicators;

Countries

China

Contacts

Public ContactWenhua Liu

the Second Affiliated Hospital of Harbin Medical University

liuwenhuaicu@163.com+86 159 0461 6690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026