pulmonary nodules
Conditions
Interventions
control (non-hydrogen absorption) group:No measure
Intervention (hydrogen absorption) group
:Inhale hydrogen or a mixture of hydrogen and oxygen through the respiratory system
Sponsors
Jinan People's Hospital (Affiliated People's Hospital, Shandong First Medical University)
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Carriers of pulmonary micronodules (with evidence of recent (less than 1 month) thin-slice CT diagnosis); 2) The diameter (long diameter) of pulmonary micronodules should be limited to 3-8mm; 3) Patients with micro/small pulmonary nodules between 8-10mm, who explicitly refuse clinical intervention; 4) The imaging size, shape, density, texture, marginal and internal characteristics of pulmonary micronodules, as well as clinical classification, are not affected, but need to be grouped evenly; 5) Age 35-80 years old, gender is not limited; The overlimit shall be appropriately expanded by the researcher according to the actual situation; 6) The physiological functions of the major organs of the body are basically normal, and the basic life is not affected; 7) The subject voluntarily agrees to participate in the observation and can cooperate closely in the intervention observation; 8) The subject himself or his legal representative agrees and signs the Informed Consent;
Exclusion criteria
Exclusion criteria: 1) Patients with an expected survival of less than 6 months; 2) Patients with cancer of any tissue or molecular type who have been diagnosed; 3) Highly suspected cancer patients with a diameter greater than 10mm; For those who strongly wish to join the group, the restrictions can be appropriately relaxed; 4) Carriers of pulmonary micronodules less than 3mm in length and diameter; For those who strongly wish to join the group, the restrictions can be appropriately relaxed; 5) Patients who do not regularly take antibacterial drugs and anti-inflammatory drugs; 6) Suspected or have a history of alcohol or drug abuse; 7) Carriers who are difficult to accurately evaluate the safety and effectiveness of hydrogen (or hydrogen and oxygen mixtures); 8) Hydrogen (or hydrogen and oxygen mixture) contraindications; 9) Patients who are bedridden for a long period of time (including, but not limited to, severe decline of various organs) 10) patients who are not considered appropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT scan, pulmonary nodules; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum immunology;Tumor marker; | — |
Countries
CHINA
Contacts
Public ContactWei Youzhen
Jinan People's Hospital (Affiliated People's Hospital, Shandong First Medical University)
Outcome results
None listed