Postoperative nausea and vomiting
Conditions
Interventions
Group OFA:Opioid free anesthesia
Group OA:Opioid anesthesia
Sponsors
Guanyun people's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Older than or equal to 18 years old; ASA class i~iii; Laparoscopic surgery under general anesthesia is scheduled, and the estimated operation duration is less than 2 hours.
Exclusion criteria
Exclusion criteria: ? Unplanned or emergency surgery; ? Those with mental illness, abnormal cognitive function, chronic pain disease, long-term use of sedative and analgesic drugs or alcohol abuse; ? Severe liver and kidney disease (child Pugh grade C, requiring renal replacement therapy); ? Severe bradycardia (HR < 50 beats / min), atrioventricular block above second degree without pacemaker, sick sinus syndrome, cardiac insufficiency (EF < 30%); ? Pregnant and lactating women; ? Those who have allergies or contraindications to the drugs used in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting (PONV); | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of PONV (Incidence of postoperative nausea and vomiting);Pain scores;Antiemetic rescue therapy;Worst pain;Need for rescue analgesia;Time to extubation; | — |
Countries
China
Contacts
Public ContactQian Long
Guanyun people's Hospital
Outcome results
None listed