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Oxycodone versus hydromorphone in patient-controlled intravenous analgesia after perianal surgery: a randomized, controlled, double-blind study

Oxycodone versus hydromorphone in patient-controlled intravenous analgesia after perianal surgery: a randomized, controlled, double-blind study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076093
Enrollment
Unknown
Registered
2023-09-25
Start date
2023-10-01
Completion date
Unknown
Last updated
2024-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia after perianal surgery

Interventions

Hydromorphone group (H group):The intravenous controlled analgesia pump contains hydromorphone (The remaining drugs are the same as the Oxycodone group)
Oxycodone Group ( O Group):The intravenous controlled analgesia pump contains oxycodone (The remaining drugs are the same as the Hydromorphone group)

Sponsors

Pidu District People’s Hospital, Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) ASAI-III level; (2) Sign informed consent (3) Patients who intend to electively undergo perianal surgery

Exclusion criteria

Exclusion criteria: (1) Patients participate in other clinical trials (2) Patients who refuse to cooperate with the study due to communication difficulties or other reasons (3)Contraindications to epidural anesthesia (patients with coagulation dysfunction and taking anticoagulant drugs) (4) History of spinal trauma or surgery (5) Preoperative history of chronic pain or long-term use of analgesics (6)Patients who refuse to follow up

Design outcomes

Primary

MeasureTime frame
NRS score at the first postoperative dressing change;

Secondary

MeasureTime frame
NRS scores at rest at 6h (T1), 12h (T2), 24h (T3), 48h (T4) and 72h (T5) after surgery;The number of PCA and the cumulative dose in 72h after surgery;Analgesic remedies and dosage;

Countries

China

Contacts

Public ContactLi Junxiang

Pidu District People’s Hospital, Chengdu

dr2002@163.com+86 183 4930 1952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026