acute coronary syndrome
Conditions
Interventions
Control group :? Control group (standard treatment group, n=268) : meeting the inclusion criteria and successfully completing infarct-related PCI, receiving placebo, subcutaneous injection, atorvastat
Intensive group:? Intensive group (standard treatment + Aliciumab, n=268) : those who met the inclusion criteria and successfully completed infarct-related PCI were given subcutaneous injection of ali
Sponsors
the second hospital of tian jin medical university tian jin china
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Over 18 years old, less than 85 years ? ACS patients who successfully underwent PCI for infarction (STEMI, NSTEMI) ? Non-blocking lesions in non-infarcted vessels (50%-70% stenosis) ? Patients who received regular statin treatment 4 weeks before inclusion but LDL-C=70mg/dl ? Patients with LDL-C=125mg/dl who did not receive regular statin treatment 4 weeks before inclusion
Exclusion criteria
Exclusion criteria: (1) Pregnant women (2) Implanted stent diameter 4.0mm (3) need to stop with the current medical condition within 24 months after enrollment, life expectancy 1.5xULN); (14) Active peptic ulcer; (15) Oral anticoagulants are also required; (16) Platelets below 100x 10 ?/L; (17) Hemoglobin below 90g/L; (18) Pregnancy or lactation; (19) Patients participating in other interventional clinical studies; (20) The researchers believe that patients who are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| all cause death;ogenic death; nonfatal myocardial infarcti;ichemic event-driven coronary revascularization; | — |
Secondary
| Measure | Time frame |
|---|---|
| percentage of atherosclerotic plaque volume in non-infarcted vessels (PAV), ;minimum fiber cap thickness in non-infarcted vessels ; | — |
Countries
China
Contacts
Public ContactXU YANMIN
the second hospital of tian jin medical university tian jin china
Outcome results
None listed