Alzheimer disease
Conditions
Interventions
early symptomatic AD patients:None
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Clinical diagnosis AD or MCI (clinical diagnosis is given by our senior Neurology according to NIA-AA standard) (2) When signing the informed consent form, the age is = 60 years old; (3) Body mass index (BMI) = 20; (4) There are data on the examination of radioactive PET tracers (Florbetapir F18, Florbetaben F18) and radioactive PET tracers (Flortaucipir F18);
Exclusion criteria
Exclusion criteria: (1) Suffering from major Nervous system disease affecting the central nervous system other than AD, which may affect cognition, including but not limited to other types of dementia, severe brain infection, Parkinson's disease, multiple Concussion, epilepsy or recurrent seizures; (2) The MRI results show evidence of significant abnormalities, suggesting the existence of another potential cause of progressive dementia (3) Received a response to A ß Active immunotherapy; (4) Suffering from serious mental illness; (5) Existence of serious or unstable diseases with an expected lifespan of less than 24 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood biomarkers;imaging markers; | — |
Countries
CHINA
Contacts
Public ContactGuofang Chen
Xuzhou Central Hospital
Outcome results
None listed