post-stroke cognitive impairment
Conditions
Interventions
Regular rehabilitation treatment group:Under the guidance of integrated platform, including general rehabilitation training such as stretch, muscle strength training, joint range of motion training an
As well as timing, orientation, memory training, 30 minutes a day, 5 days a week, a total of 3 weeks of intervention.
Transcranial direct current stimulation group:On the basis of routine training, the patients were treated with tDCS using Transcranial direct-current stimulation equipment from of Wuhan Ireed Medical
The transcranial magnetic stimulation group was repeated:On the basis of routine training, the figure-8 coil of Ired's transcranial magnetic stimulation instrument was used for TMS treatment.Patients
Sponsors
Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.The diagnosis of stroke was based on the diagnostic essentials of major cerebrovascular diseases in China 2019 and confirmed by CT or MRI examination. They were in accordance with the diagnostic criteria of PSCI in the expert consensus on management of poststroke cognitive impairment 2021. 2. MMSE<24(high school and above education). MMSE<20(primary school education). MMSE<17(illiteracy). or MOCA< 26. 3.The course of disease was more than 2 weeks and the first stroke was within 6 months 4.Stable vital signs, no severe aphasia, vision, hearing, cognitive impairment, to complete the study program. 5.Age over 60 years old. 6. If cognitive or antidepressant drugs are used, the dose is not adjusted within 1 week; 7. Participate voluntarily and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Previous history of brain diseases other than cerebrovascular diseases, such as brain trauma, chronic head injury, brain infection, etc. 2.Implants of metal or electronic devices such as artificial pacemaker, cochlear implants, deep brain stimulators, aneurysm clips, post-ventriculoperitoneal shunt internal fixation devices, etc. 3.Unstable heart disease, hypertension and other serious diseases that may affect the study. 4.severe aphasia, visual and hearing impairment. 5.patients with cognitive impairment due to other causes before stroke, 6. Patients with contraindications to RTMS or tDCS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment, MoCA;Mini-mental State Examination, MMSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| activities of daily living, ADL;Depression status/degree;brain function; | — |
Countries
China
Contacts
Public ContactYulong Bai
Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Outcome results
None listed