Acute traumatic coagulation disease
Conditions
Interventions
research group (Antifibrinolysis was treated with tranexamic acid):None
Sponsors
Taicang First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Patients over 18 years old; (2) Trauma patients have one of the following conditions: SBP 1 or clinical manifestations of shock.
Exclusion criteria
Exclusion criteria: (1) Patients with previous coagulation disorders and long-term oral anticoagulant drugs; (2) Patients with a history of alcoholism, malignant tumor, organ dysfunction, venous thromboembolism, etc.; (3) Patients with DIC and other contraindications in the use of anti-fibrinolytic drugs; (4) ISS 3 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TAT,PIC,t-PAIC-1,TM;LY30;24-hour mortality;28-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reaction time;kinetic time;a angle;maximum amplitude;PT;APTT;D-dmier;fibrinogen;TT;PLT;Mechanical ventilation time;Incidence of venous thromboembolism;Incidence of multiple organ dysfunction;24-hour blood transfusion volume;Length of ICU stay ICU;Total hospitalization days;Total hospital expenses; | — |
Countries
China
Contacts
Public ContactLuping Zhang
Taicang First People's Hospital
Outcome results
None listed