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Study on the mechanism and application of lower limb motor imagination in patients with paralysis

Study on the mechanism and application of lower limb motor imagination in patients with paralysis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076059
Enrollment
Unknown
Registered
2023-09-22
Start date
2022-01-25
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paralysis (Stroke & Spinal cord injury)

Interventions

Stroke group:None
Normal group:None

Sponsors

General Hospital of Western War Zone
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Stroke patients with hemiplegia: 1) meet the diagnostic criteria for ischemic stroke; 2) Participants enrolled within six months; 3) Age between 18 and 85 years old (gender no special requirements); 4) The skin remains intact and the limbs are structurally intact; 5) The subject is able to understand the purpose of the study, demonstrate sufficient compliance with the study protocol, and sign the informed consent. Patients with spinal cord injury and paraplegia: 1) were diagnosed by the researchers as recovering from spinal cord injury, and the injured plane was thoracic and lumbar segments; 2) The neural plane of patients with Spinal cord Injury was evaluated using the American Spinal Injury Association (ASIA) International Standard neurological classification of spinal cord injury (ASIA grade C or D); 3) Age between 18 and 85 years old (gender no special requirements); 4) The skin remains intact and the limbs are structurally intact; 5) The subject is able to understand the purpose of the study, demonstrate sufficient compliance with the study protocol, and sign the informed consent. Normal person: 1) no previous history of epilepsy, cerebrovascular disease and mental illness, no organic brain lesions; 2) Generally in good condition, with no serious primary or secondary diseases except general chronic underlying diseases; 3) Age between 18 and 85 years old (gender no special requirements); 4) The skin remains intact and the limbs are structurally intact; 5) The subject is able to understand the purpose of the study, demonstrate sufficient compliance with the study protocol, and sign the informed consent.

Exclusion criteria

Exclusion criteria: Stroke patients with hemiplegia: 1) previous history of epilepsy; 2) suffering from mental illness; 3) Previous history of stroke; 4) Craniotomy or cranioplasty was performed; 5) National Institutes of Health Stroke Scale (NIHSS) score greater than 20 points; 6) Cortical infarction was confirmed by imaging examination; (7) Stroke patients who have been confirmed by examination to be caused by brain tumors, brain exogenesis, blood diseases, etc.; 8) Sedative hypnosis, antiepileptic and psychotic drugs were used within 24h before EEG; 9) Disorder of consciousness, aphasia, severe dementia, severe vision and hearing impairment can not cooperate with clinical investigators; 10) Complicated with serious cardiovascular, high blood pressure, digestive, hematopoietic system, liver, kidney and other primary diseases, vital signs are unstable, difficult to cooperate with the examination. Patients with spinal cord injury and paraplegia: 1) previous history of epilepsy; 2) suffering from mental illness; 3) Previous history of stroke; 4) Imaging examination confirmed cortical infarction; 5) Stroke patients confirmed by examination to be caused by brain tumors, brain exogenesis, blood diseases, etc.; 6) Sedative hypnosis, antiepileptic and psychotic drugs were used within 24h before EEG; 7) Consciousness disorder, aphasia, severe dementia, severe vision and hearing impairment can not cooperate with clinical investigators; 8) Complicated with serious cardiovascular, high blood pressure, digestive, hematopoietic system, liver, kidney and other primary diseases, vital signs are unstable, difficult to cooperate with the examination. Normal people: 1) History of epilepsy; 2) suffering from mental illness; 3) Previous history of stroke; 4) Craniotomy or cranioplasty was performed; 5) Sedative hypnosis, antiepileptic and psychotic drugs were used within 24h before EEG; 6) Disorder of consciousness, aphasia, severe dementia, severe vision and hearing impairment can not cooperate with clinical investigators; 7) Complicated with serious cardiovascular, high blood pressure, digestive, hematopoietic system, liver, kidney and other primary diseases, vital signs are unstable, difficult to cooperate with the examination.

Design outcomes

Primary

MeasureTime frame
Brain network;

Secondary

MeasureTime frame
Event-related potential;Event-related (de)synchronization;

Countries

China

Contacts

Public ContactWang Wenchun

General Hospital of Western Theater Command of PLA

wwc1977@foxmail.com+86 189 0806 9418

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026