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Neural mechanisms of task-oriented training with intelligent mirror gloves combined with low-frequency repetitive transcranial magnetic stimulation to promote hand function recovery in stroke patients

Neural mechanisms of task-oriented training with intelligent mirror gloves combined with low-frequency repetitive transcranial magnetic stimulation to promote hand function recovery in stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076058
Enrollment
Unknown
Registered
2023-09-22
Start date
2023-09-23
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CVA

Interventions

Normal group:Routine rehabilitation training
Mirror group:Mirror Smart Glove Task Oriented Training
rTMS group:Low frequency rTMS therapy
Combined group:Mirror Smart Glove Task Oriented Training+Low frequency rTMS therapy

Sponsors

Northern Jiangsu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) The first onset was unilateral hemiparesis and diagnosed as subcortical injury by CT or MRI;(2) Age 18-80 years old; (3) Duration of the disease was from 7 days to 3 months after the onset of the disease; (4) The affected hand had Brunnstrom staging II-III; (5) The condition was stable, conscious, with Montreal cognitive assessment (MoCA) =26 points, and able to cooperate with the completion of required rehabilitation training; (6) The patients or their family members gave their informed consent to this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) patients with severe cardiac, pulmonary, hepatic, renal, and other important organ dysfunction; (2) patients with previous Parkinson's disease, peripheral neuropathy, and other motor dysfunction; (3) patients with a history of metallic implants or pacemaker implantation in the skull; (4) patients with malignant tumors; (5) patients who have taken or are currently taking medications to alter the excitability of the cerebral cortex; and (vi) patients with improved Ashworth index scores of the flexor and extensor muscle groups of the hand that are > grade 1+.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Rating Scale Hand and Wrist Component Scores;

Secondary

MeasureTime frame
Wolf Motor Function Test Scale;Hand motor function status score;Total active finger mobility;TMS-MEP;fMRI;

Countries

China

Contacts

Public ContactXing Jin

Northern Jiangsu People's Hospital

yzjinxing@qq.com+86 180 5106 2457

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026