Skip to content

Esketamine reduces the decrease in heart rate during hysteroscopic surgery

Esketamine reduces the decrease in the center rate of hysteroscopic surgery: a single center, prospective, double-blind, randomized controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076050
Enrollment
Unknown
Registered
2023-09-22
Start date
2023-09-30
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopic surgery

Interventions

esketamine anesthesia group:The anesthesia induction plan is propofol 2.5mg/kg+esketamine 0.3mg/kg iv
sufentanil anesthesia group:The anesthesia induction plan is propofol 2.5mg/kg+sufentanil 0.2ug/kg iv

Sponsors

Weihai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ? Female aged 18-65; ? No serious comorbidities, such as unstable angina and poor control of severe hypertension; ? Able to cooperate in communication and complete follow-up indicators; ? Sign an informed consent form;

Exclusion criteria

Exclusion criteria: ? Previous history of major surgeries, such as heart surgery, craniotomy, etc; ? There are contraindications to the use of ketamine, such as severe hypertension and poorly controlled asthma; ? Allergy to research medication; ? Patients with mental illness cannot cooperate with follow-up;

Design outcomes

Primary

MeasureTime frame
Patient's systolic blood pressure, diastolic blood pressure, mean blood pressure, and heart rate;

Secondary

MeasureTime frame
Patient's placement of laryngeal mask (no resistance, mild resistance, significant resistance, unable to insert);Total demand for propofol and remifentanil during patient anesthesia maintenance phase;Time required for the patient to recover from surgery;The patient experiences nausea, vomiting, restlessness and delirium after resuscitation;Patient pain after resuscitation (NRS scoring system);Patient hospitalization time and expenses;

Countries

China

Contacts

Public ContactGuan Yingchao

Weihai Municipal Hospital

Gvwalgiya1993@foxmail.com+86 156 5013 8341

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026