Heart failure with preserved ejection fraction
Conditions
Interventions
Linggui group:Combination of conventional western medicine treatment and Linggui Qihua Granule
Control group:Conventional western medicine treatment
Sponsors
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Comply with the early diagnostic criteria of the guidelines; (2) The underlying disease causing HFpEF is hypertension and/or coronary heart disease (including coronary microcirculation disorders) in patients; (3) Traditional Chinese medicine syndrome differentiation is in line with the unfavorable syndrome of gasification, and there are cases where water consumption stops internally; (4) Age: 40-85 years old; (5) Volunteer to participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) For patients with drug allergies in this study; (2) Patients with other types of diseases that lead to HFpEF (such as cardiomyopathy, diseases related to right heart and pulmonary hypertension, and extracardiac diseases); (3) Pregnant or lactating women; (4) Patients with mental illness or poor compliance; (5) Individuals with severe cognitive impairment or other reasons that prevent communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six-minute walk test;The Kansas City Cardiomyopathy Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM symptom score;N-terminal pro-Btype natriuretic peptide;Left atrial diameter;Left ventricular end diastolic dimension;Interventricular septal thickness;Ratio of left ventricular peak velocity early diastolic filling to peak velocity of late diastolic filling;Atrial systolic left ventricular filling peak velocity; | — |
Countries
China
Contacts
Public ContactDongguoju
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed