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The correlation of plasma PAR1, p-ERM and ERM with early diagnosis and prognosis evaluation in patients with sepsis

The correlation of plasma PAR1, p-ERM and ERM with early diagnosis and prognosis evaluation in patients with sepsis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076040
Enrollment
Unknown
Registered
2023-09-22
Start date
2023-10-01
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

case series:nil

Sponsors

Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medical
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Aged >=18 years; (2) Signed informed consent; (3) Patients diagnosed with sepsis or septic shock according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); (4) Healthy volunteers are screened by the medical examination center.

Exclusion criteria

Exclusion criteria: (1) Treatment for no more than 24 hours of death or discharge; (2) Participate in other researchers at the same time; (3) pregnancy or lactation; (4) complicated with other acute non-infectious acute inflammatory response syndrome, organ injury or shock; (5) The patient had used antibiotics, fluid resuscitation and other treatments before admission.

Design outcomes

Primary

MeasureTime frame
PAR1;P-moesin;P-Ezrin;P-Radixin;moesin;Ezrin;Radixin;SOFA;APACHE II;

Secondary

MeasureTime frame
PCT;CRP;Lac;

Countries

China

Contacts

Public ContactJinhong Wu

Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medical

wujinhong568@163.com+86 135 0571 8066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026