McCune-Albright syndrome
Conditions
Interventions
Sponsors
the First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patients with typical clinical manifestations suspected of MAS (=1 of the three major diseases of Cafe-au-lait, precocious puberty (hyperfunction of endocrine glands ), and bone fibrous dysplasia) and pathogenic variation of the GNAS gene. 2. Patients diagnosed MAS with the three typical main symptoms but the GNAS1 gene mutations were not detected.
Exclusion criteria
Exclusion criteria: 1, Patients have less than three typical main symptoms ( Cafe-au-lait, precocious puberty(hyperfunction of endocrine glands), and bone fibrous dysplasia) and the GNAS1 gene mutations were not detected. 2. Patients with MAS were reluctant to join the cohort of researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cafe-au-late spots;hyperfunction of endocrine glands;bone fibrous dysplasia; | — |
Countries
China
Contacts
Public ContactWang Chunlin
the First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed