Allergic rhinitis
Conditions
Interventions
Allergic rhinitis group:Specific subcutaneous immunotherapy for allergic rhinitis
Non allergic rhinitis group:Non
Sponsors
Fuqing City Hospital of Fujian
Eligibility
Sex/Gender
All
Age
5 Years to 50 Years
Inclusion criteria
Inclusion criteria: ? Symptoms: Paroxysmal sneezing, clear water like runny nose, nasal itching, and nasal congestion, with symptoms lasting or accumulating for more than 1 hour per day On, it may be accompanied by eye symptoms such as tears, itching, and redness; ? Physical signs: Common nasal mucosa pale, edema, and watery secretions in the nasal cavity; ? Allergen testing: At least one allergen SPT and/or serum specific IgE positive, or nasal challenge test positive. And comply with Diagnostic criteria for moderate to severe persistent AR: Symptoms are severe or severe, have a significant impact on quality of life, and the onset of symptoms is = 4 days week,Continuation for = 4 weeks. ? Receive subcutaneous desensitization immunotherapy.
Exclusion criteria
Exclusion criteria: ? Those under 5 years old or over 50 years old; ? Individuals with uncontrolled paroxysmal asthma; ? Patients with severe mental and psychological disorders; ? Patients with malignant tumors or other autoimmune diseases; ? Patients with liver, gallbladder or intestinal related diseases ? Pregnant patients; ? Patients who cannot accept subcutaneous immunotherapy pose related risks and complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum bile acid;TNSS;VAS;Drug score;RQLQ;PHQ-9 ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum IgE; Serum IgG4; | — |
Countries
China
Contacts
Public ContactShancai He
Fuqing City Hospital of Fujian
Outcome results
None listed