postoperative analgesia
Conditions
Interventions
Experimental group:The experimental group used closed-loop feedback program control system analgesic pump after surgery
Control group:The control group used ordinary intravenous automatic analgesic pump after surgery
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients undergoing knee replacement surgery under elective tracheal intubation and general anesthesia 2) ASA Level II-III 3) Age 65-80 4) Volunteer to participate in this research project
Exclusion criteria
Exclusion criteria: 1) Esketamine, oxycodone intolerance 2) Taking strong opioids or monoamine oxidase inhibitors 2 weeks before the study 3) History of alcoholism and drug abuse 4) BMI>30 5) Sleep apnea syndrome 6) Severe liver and kidney diseases 7) Mental and physical illness, unable to communicate and understand
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions (nausea, vomiting, dizziness, headache, pruritus, lethargy, hallucinations, respiratory depression) within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS score at rest and activity at 24h and 48h after surgery;Pain rating 1 month after surgery;Number of pain relief cases in 24h;number of PCIA compressions;score of postoperative sleep quality (1 point = good sleep, 2 points = disturbed sleep, 3 points = nightmares, 4 points = insomnia);satisfaction (0 points = unsatisfactory, 1 point = satisfactory, 2 points = satisfactory); | — |
Countries
China
Contacts
Public ContactChaokun Zeng
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed