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Validation of an integrated platform for early warning and intervention of elderly awareness/cognitive impairment assessment Part I: Clinical efficacy evaluation and mechanism of tDCS combined with rTMS in elderly patients with mild cognitive impairment Explore)

Validation of an integrated platform for early warning and intervention of elderly awareness/cognitive impairment assessment Part I: Clinical efficacy evaluation and mechanism of tDCS combined with rTMS in elderly patients with mild cognitive impairment Explore)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076024
Enrollment
Unknown
Registered
2023-09-22
Start date
2023-09-23
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment,MCI

Interventions

Regular cognitive training group:Routine cognitive training: therapist one-on-one orientation and memory training, 30 minutes a day, 5 days a week, a total of 3 weeks of intervention
Transcranial direct current stimulation group:The transcranial direct current stimulation therapy instrument of Wuhan Ireed Medical Equipment New Technology Co., Ltd. was used in the tDCS treatment of
The transcranial magnetic stimulation group was repeated:In the single magnetic stimulation group, the figure-8 coil of Ired's transcranial magnetic stimulation instrument was used for TMS treatment.

Sponsors

Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Mild cognitive impairment (20 points =MoCA<26 points, years of education =12 years, score plus 1 point); 2. Stable vital signs, no history of craniocerebral injury, no severe aphasia, visual, auditory, cognitive impairment, can cooperate with the completion of the study program; 3. Age over 60 years old; 4. If cognitive or antidepressant drugs are used, the dose is not adjusted within 1 week; 5. Participate voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. History of epilepsy or mental disorders, craniotomy, skull defect; 2. There are metal or electronic device implants (such as cardiac pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, internal fixation devices after ventriculoperitoneal SHTS, etc.); 3. Damaged skin integrity at the electrode placement site, or allergic to electrode gels or adhesives; 4. Severe aphasia, visual and hearing impairment; 5. Unstable heart disease, high blood pressure, and other serious conditions that could affect the study.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment, MoCA;Mini-mental State Examination, MMSE;

Secondary

MeasureTime frame
activities of daily living, ADL;Depression status/degree;brain function;

Countries

China

Contacts

Public ContactYulong Bai

Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University

dr_baiyl@fudan.edu.cn+86 135 2118 6606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026