Chronic pain depression comorbidity
Conditions
Interventions
Chronic pain with depression group:None
Sponsors
First Affiliated Hospital of the Air Force Medical University; Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Age:18-60 years old (the boundary value), gender is not limited; (2) Patients with spinal cord injury and peripheral pain (soft tissue injury or bone and joint injury causing pain); (3) Patients with NRS score > 3 and pain lasting for more than 1 month.
Exclusion criteria
Exclusion criteria: (1) Women whose pregnancy tests (only women of childbearing age) are positive; (2) Patients with severe cardiovascular, lung, immune system, skin, skeletal muscle, and nervous system diseases that the researchers considered unsuitable for inclusion; (3) Patients addicted to alcohol and drugs (long-term use and dependence on alcohol and drugs); (4) Patients with neurological diseases (stroke, epilepsy) and family history of anxiety and depression; (5) Patients with vitamin A allergy; (6) Patients who have used acne cream (containing isotretinoin) and vitamins (containing vitamin A) in the past three months; (7) Participants who are considered inappropriate to participate in this clinical trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinoic Acid;NRS;PHQ-9 and HAMD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vitamin A;Istretinoin;Retinene;Retinol; | — |
Countries
China
Contacts
Public ContactLi Zhenzhen
First Affiliated Hospital of the Air Force Medical University; Air Force Medical University
Outcome results
None listed