Heart Failure
Conditions
Interventions
Shexiang Baoxin Pill:conventional therapy + Shexiang Baoxin Pill (270 mg/d)
Placebo:conventional therapy + Placebo (270 mg/d)
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age = 18 and = 80 years old, regardless of gender. 2) According to the 2021 ESC Heart Failure Guidelines, HFpEF was diagnosed, including clinical symptoms and signs of heart failure. LVEF = 50%, with evidence of cardiac structural changes (left atrial enlargement or left ventricular hypertrophy) and elevated left ventricular filling pressure. 3) The New York Heart Association cardiac function grading is level II-IV. 4) The patient agrees to participate in the study and signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1) There is severe dysfunction of important organs such as liver and kidney. 2) Acute decompensated heart failure. 3) Acute myocarditis, pericardial disease, valvular heart disease, primary cardiomyopathy, congenital heart disease, primary pulmonary hypertension, or secondary severe pulmonary hypertension. 4) During pregnancy, preparation, or breastfeeding. 5) Individuals who are allergic to the ingredients contained in Musk Heart Protecting Pills or medications. 6) Those with a life expectancy of less than 2 years. 7) Individuals who are receiving any investigational treatment other than the drugs used in this study. 8) Those with poor dependency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial energy expenditure; | — |
Secondary
| Measure | Time frame |
|---|---|
| LVEDD;LVEF;LVMI;cESS; | — |
Countries
China
Contacts
Public ContactGang Li
Sichuan Provincial People's Hospital
Outcome results
None listed