acute cerebral infarction
Conditions
Interventions
experimental group:Treatment with tirofiban after imaging examination
control group:Intensive lipid-lowering therapy
Sponsors
Tianjin TEDA hospital
Eligibility
Sex/Gender
All
Age
75 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) The patient meets the diagnostic criteria for acute cerebral infarction in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke, and all patients have confirmed the presence of infarcted lesions through cranial CT and MRI examinations; (2) The time from onset to admission for treatment is 4.5-8.0 hours; (3) NIHSS score = 6 points at onset; (4) The mRS score before this onset was 0.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) presence of intracranial space occupying, intracerebral hemorrhage or Subarachnoid hemorrhage; (2) Emergency whole brain angiography examination showed severe stenosis or occlusion of the cerebral blood supply arteries (internal carotid artery, anterior, middle, posterior cerebral artery, basilar artery, vertebral artery); (3) Confirmed by cranial MRI examination that the infarct site does not match the responsible blood vessel for treatment; (4) Accompanied by severe heart, lung, kidney, and liver dysfunction; (5) Coma; (6) Contrast agent allergy; (7) Has a tendency for severe bleeding; (8) There are other contraindications for cerebral angiography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS scores;mRS scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| PT APTT TT FIB; | — |
Countries
China
Contacts
Public ContactZaiyu Guo
Tianjin TEDA hospital
Outcome results
None listed