breast cancer
Conditions
Interventions
no:no
no:No
Sponsors
the First Affiliated Hospiof Army Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age 18-65 years; female; 2) Primary treatment without prior breast surgery; 3) Pathologically confirmed breast cancer at the time of initial diagnosis, with assessment of stage cN+ confirmed by penetrating pathology; 4) All patients receive 4-6 cycles of neoadjuvant chemotherapy. The regimen was mainly based on anthracyclines and/or paclitaxel. If the patient's immunohistochemistry was suggestive of HER-2 positivity, anti-human epidermal growth factor receptor 2 (HER-2) targeted therapy was added; 5) All patients completed NAC as planned before surgery.
Exclusion criteria
Exclusion criteria: 1) Have not completed neoadjuvant therapy for various reasons; 2) Having undergone multiple breast or axillary surgeries; 3) Patients with the presence of other tumours or the presence of distant metastases; 4) Patients with incomplete case reports (in the retrospective cohort).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| patient's menstrual status;Clinical stage;Tumor size and morphological characteristics ;MRI:First Order Statistics and Texture Features Based on Original Images;MRI:First order statistics and texture features extracted from transformed images based on wavelet, exponential, and square root filtering;BI-RADS: tumor size;BI-RADS: Tumor boundary;BI-RADS: Tumor quadrant;metastasis in lymph nodes ;Number of lymph nodes;Number of metastatic lymph nodes;chemotherapy response in lymph nodes; | — |
Countries
China
Contacts
Public ContactPeng Tang
the First Affiliated Hospitalof Army Medical University
Outcome results
None listed