pulmonary complications
Conditions
Interventions
group of peep titration :The experimental group was PEEP titration group, and the PEEP value was titrated according to the optimal lung compliance. The specific operations were as follows: When the ti
group of routine lung protective ventilation :The control group was the conventional lung protection ventilation group, and the tidal volume was 6ml?kg-1. PEEP is 5cmH2O. During the operation, PETCO2
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: ASA rating I-III Age 60-85 years old BMI 18.5-30kg/m2 There were no obvious abnormalities in cardiac, lung, liver and renal function before operation The operation time is 2-5h No history of chronic lung disease Preoperative chest radiograph or CT was normal
Exclusion criteria
Exclusion criteria: He received ventilator treatment within one month Diagnosed or suspected sleep apnea syndrome History of severe lung disease such as COPD, lung infection, bronchiectasis, asthma, etc There are thoracic and intrathoracic diseases such as thoracic malformations, mediastinal tumors, chest tumors, etc Severe neuromuscular disease Recent use of immunosuppressive therapy (<3 months) Leukocyte elevation of unknown cause People with immune system diseases Patients with language or communication difficulties or who refuse to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of pulmonary complications at 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative respiratory mechanics indicators;Intraoperative hemodynamic indicators;hospital day;ICU hospitalization day;30 day postoperative mortality rate; | — |
Countries
China
Contacts
Public ContactRurong Wang
Department of Anaesthesiology, West China Hospital, Sichuan University,Chengdu,610041, China.
Outcome results
None listed