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A prospective observational cohort study of cognitive impairment associated with cerebral small vessel disease based on optical coherence tomography angigraphy-labeled

A prospective observational cohort study of cognitive impairment associated with cerebral small vessel disease based on optical coherence tomography angigraphy-labeled

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075909
Enrollment
Unknown
Registered
2023-09-19
Start date
2023-09-20
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lacunar cerebral infarction

Interventions

Case series:NA

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: 18-75 years old, gender is not limited 2: Patients with clinical manifestations of lacunar cerebral infarction within 3 months of onset (NIHSS score = 3) with corresponding lesions on MRI of the head 3: Participants are generally in good condition, conscious, able to complete relevant assessment scales, and able to receive long-term follow-up.

Exclusion criteria

Exclusion criteria: 1: Retinopathy with congenital eye disease, history of intraocular surgery, presence of significant lens opacity or evidence of any macular disease, previous diagnosis of glaucoma, vitreoretinal disease, uveitis, and diabetes 2: Patients with a history of other neurological or psychiatric disorders, coagulopathy, head trauma, alcohol or drug addiction, or depression are also excluded 3: Exclusion of cognitive dysfunction due to other causes. 4: The investigators considered it inappropriate for inclusion

Design outcomes

Primary

MeasureTime frame
Minimum Mental State Examination Score;

Secondary

MeasureTime frame
Imaging score for cerebral small vessel disease;

Countries

CHINA

Contacts

Public ContactWU YUNCHENG

Shanghai General Hospital

drwu2006@163.com+86 189 3031 3198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026