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Comparison of the analgesic effect of bilateral intertransverse process block and bilateral thoracic paravertebral block in laparoscopic total hysterectomy: a randomized, controlled, non-inferiority study

Comparison of the analgesic effect of bilateral intertransverse process block and bilateral thoracic paravertebral block in laparoscopic total hysterectomy: a randomized, controlled, non-inferiority study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075908
Enrollment
Unknown
Registered
2023-09-19
Start date
2023-09-20
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic total hysterectomy

Interventions

Thoracic paravertebral block (TPVB group):Bilateral thoracic paravertebral block was performed before anesthesia, and 0.375% ropivacaine 20mL was injected on each side
Intertransverse process block (ITP group):Bilateral intertransverse block was performed before anesthesia, and 0.375% ropivacaine 20mL was injected on each side

Sponsors

Anhui Provincial Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing laparoscopic hysterectomy: 1) aged 18-65 years; 2) signed informed consent; 3) American Society of Anesthesiologists (ASA) grade I-II.

Exclusion criteria

Exclusion criteria: 1) any relevant major cardiac or respiratory disease, hematologic disease or disturbance of coagulation parameters, pre-existing major organ dysfunction (such as liver or kidney failure); 2) general contraindications of nerve block; 3) any contraindication to propofol, sufentanil or sevoflurane; 4) Allergic history to amide local anesthetics; 5) patients with previous laparotomy history; 6) patients with previous somatosensory disorders; 7) patients with spinal anatomical deformity; 8) emergency surgery patients; 9) a history of chronic pain; 10) patients with long history of opioid use; 11) patients with mental illness or inability to understand NRS scores.

Design outcomes

Primary

MeasureTime frame
NRS for pain on movement 12 hours after surgery;

Secondary

MeasureTime frame
Success rate of block;NRS score for resting state and cough;MAP;HR;Plasma levels of IL-6, NE, E, and Cor;Total opioid use;Degree of nausea and vomiting;Incidence of complications;Quality of patient recovery;

Countries

China

Contacts

Public ContactJi Tianzhen, Xie Lei

Anhui Provincial Maternal and Child Health Hospital

xielei169@163.com+86 137 3927 6825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026