Laparoscopic total hysterectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing laparoscopic hysterectomy: 1) aged 18-65 years; 2) signed informed consent; 3) American Society of Anesthesiologists (ASA) grade I-II.
Exclusion criteria
Exclusion criteria: 1) any relevant major cardiac or respiratory disease, hematologic disease or disturbance of coagulation parameters, pre-existing major organ dysfunction (such as liver or kidney failure); 2) general contraindications of nerve block; 3) any contraindication to propofol, sufentanil or sevoflurane; 4) Allergic history to amide local anesthetics; 5) patients with previous laparotomy history; 6) patients with previous somatosensory disorders; 7) patients with spinal anatomical deformity; 8) emergency surgery patients; 9) a history of chronic pain; 10) patients with long history of opioid use; 11) patients with mental illness or inability to understand NRS scores.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS for pain on movement 12 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of block;NRS score for resting state and cough;MAP;HR;Plasma levels of IL-6, NE, E, and Cor;Total opioid use;Degree of nausea and vomiting;Incidence of complications;Quality of patient recovery; | — |
Countries
China
Contacts
Anhui Provincial Maternal and Child Health Hospital