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A Retrospective Study on the Effectiveness, Safety, and Indications of blood protection in Acute Normovolemic Hemodilution in Total Knee Arthroplasty

A Retrospective Study on the Effectiveness, Safety, and Indications of blood protection in Acute Normovolemic Hemodilution in Total Knee Arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075901
Enrollment
Unknown
Registered
2023-09-19
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

ANH Group:N/A
Non-ANH Group:N/A

Sponsors

Joint Osteopathy Surgery, Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 60-80 years old; 2. In patients with advanced knee osteoarthritis, the knee space is significantly narrowed, painful and limited in activity, and conservative treatment is ineffective, requiring total knee replacement; 3. The patient's physical condition can tolerate surgery; 4. Patients undergoing total knee arthroplasty in our department;

Exclusion criteria

Exclusion criteria: 1. Patients with severe coagulopathy; 2. Patients with severe heart, lung, liver and kidney failure; 3. Patients with toxemia; 4. Patients with rheumatism and other systemic diseases; 5. Severe infection occurred before surgery; 6. Patients undergoing non-unilateral TKA surgery.

Design outcomes

Primary

MeasureTime frame
Theoretical loss of red blood cells;

Secondary

MeasureTime frame
Hb;PLT;WBC;HSCRP;ESR-T;Cr;Urea;CysC;eGFR;GGT;ALT;AST;RPP;DP;Alb;VAS;ROM;WOMAC;

Countries

China

Contacts

Public ContactLijun Lin

Joint Osteopathy Surgery, Zhujiang Hospital, Southern Medical University

gost1@smu.edu.cn+86 138 2215 3869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026