Thyroid cancer
Conditions
Interventions
Gold Standard:Postoperative histopathological or clinical comprehensive diagnosis.
Index test:Biomarkers: Gene mutation detection based on joint probe anchored polymerization sequencing technology.
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The sample type is a fine-needle biopsy sample of thyroid nodules, which must meet any of the following requirements: (1) Patients with benign and malignant thyroid nodules (Bethesda Type III, IV and ?) could not be identified by cytopathological examination after fine needle puncture with combined histopathological/clinical diagnosis results; (2) Bethesda Type II thyroid nodule patients with benign lesions as a result of histopathological/clinical comprehensive diagnosis after surgery; (3) Postoperative histopathological findings were malignant Bethesda type VI thyroid cancer patients.
Exclusion criteria
Exclusion criteria: 1. The samples are not collected, stored and processed according to the specified requirements; 2. The sample does not meet the test requirements; 3. Repeated case samples; 4. Samples that the researchers think are not suitable for further clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive coincidence rate and 95% CI;Negative coincidence rate and 95% CI;Total compliance rate and 95% CI;sensitivity;Specificity;Kappa value; | — |
Countries
China
Contacts
Public ContactZhiyan Liu
Shanghai Sixth People's Hospital
Outcome results
None listed