pulmonary complications
Conditions
Interventions
The intervention group:individual positive end expiratory pressure
The control group:fixed positive end expiratory pressure of 5cmH2O
Sponsors
Qilu Hospital of Shandong University Dezhou Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Age 18-80 years old; ? ASA I to III; ? BMI 10 pack*year and no smoking cessation within 3 years (pack*year=number of packs smoked per day * number of years smoked); ? General anesthesia is scheduled for non cardiac or non neurosurgical surgeries, with an estimated surgical duration greater than 2 hours.
Exclusion criteria
Exclusion criteria: ? Patients who require one-lung ventilation during surgery; ? Patients with heart failure (NYHA III-IV); ? Patients with severe liver and kidney diseases and coagulation disorders; ? Patients with increased intracranial pressure and pneumothorax or pulmonary bullae; ? Patients with severe, extremely severe restrictive or obstructive ventilation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory mechanics;Hemodynamics;Arterial blood gas;The incidence of postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactJianbo Wu
Qilu Hospital of Shandong University Dezhou Hospital
Outcome results
None listed