Primary osteoporosis
Conditions
Interventions
control:none
Osteoporosis 1:none
Osteoporosis 2:none
Sponsors
Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for cases of osteoporosis (1) Women aged 50-70 who have experienced natural menopause and have experienced menopause for more than 1 year. (2) The bone density examination indicates a decrease of more than 2.5 standard deviations in the mean bone density of the 2nd to 4th vertebrae of the lumbar spine, hip bone density, or femoral neck bone density at any one location. (3) Conforming to the diagnosis of kidney deficiency or spleen kidney deficiency in traditional Chinese medicine. (4) Volunteer to be the subject and sign an informed consent form. Inclusion criteria for healthy subjects (1) Healthy women aged 18-30. (2) The bone density is normal. (3) Eat regularly and have a normal routine. (4) Volunteer to be the subject and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria for cases of osteoporosis (1) Patients with severe primary diseases such as cardiovascular, hematopoietic, and neuropsychiatric systems. (2) Patients who have received hormone replacement (HRT) or calcitonin treatment within the past 3 months, or have received bisphosphonate treatment for 15 consecutive days or more within the past 6 months. Exclusion criteria for healthy subjects (1) Take any medication or health products within the past 3 months. (2) Recently, there have been gastrointestinal symptoms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota spectrum;metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| bone metabolism;sex hormone; | — |
Countries
China
Contacts
Public ContactYongfang Zhao
Shanghai University of Traditional Chinese Medicine
Outcome results
None listed