gingivitis
Conditions
Interventions
gingivitis group:antimicrobial peptide mouthwash
health group:antimicrobial peptide mouthwash
Sponsors
School and Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1) Good overall health; 2) Aged 18-35 years old; 3) Teeth and gums should be checked first, and qualified participants can participate in this study; 4) Do not use any antibiotics and antibiotics 1 month before the study; 5) Agree to participate in the clinical study and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1)Participate in other clinical studies; 2)Use phenol-containing or peppermint flavoring products, such as non-test mouthwash, toothpaste, chewing gum, etc.; 3)History of allergy to this product and its ingredients; 4)AIDS, diabetes, hypertension and other infectious diseases and systemic diseases; 5)For those with periodontitis or mouth ulcers, wear dentures or orthodontic accessories; 6)Smoking or using tobacco products; 7)Use antihistamines for nearly 1 week or immunosuppressants or antibiotics for nearly 1 month; 8)The presence of any disease or condition that the study investigator believes may affect the examination procedure and the subject's safe completion of the study; 9)Women during pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plaque index; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Saliva PH;nitrate;bleeding on probing; | — |
Countries
China
Contacts
Public ContactShao Jinlong
School and Hospital of Shandong University
Outcome results
None listed