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The study of orthokeratology lenses combined with atropine eye drops to control the development of myopia in adolescents

The study of orthokeratology lenses combined with atropine eye drops to control the development of myopia in adolescents

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075865
Enrollment
Unknown
Registered
2023-09-18
Start date
2023-09-20
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

Control:Glasses
Experimental 1:Glasses+atropine
Experimental 2:orthokeratology+atropine
Experimental 3:reduced the back optic zone diameter orthokeratology+atropine
Experimental 4:orthokeratology
Experimental 5:increased compression factor orthokeratology
Experimental 6:Peripheral defocusing glasses
Experimental 7:reduced the back optic zone diameter orthokeratology

Sponsors

The First Affiliated Hospital of Baotou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 12 Years

Inclusion criteria

Inclusion criteria: (1) Age 8-12 years old (2) After astigmatism and refraction, the diopter is -1.00D ? -5.00D, and the binocular astigmatism is = -1.50D (3) Best corrected visual acuity for both eyes = 4.9 (4) Normal anterior segment, eye position, fundus, and intraocular pressure (intraocular pressure 10-21mm Hg) (5) There is no history of myopia control treatment such as wearing contact lenses or atropine eye drops in the past 3 months, and there are no contraindications for wearing corneal shaping lenses. The overall condition is normal (6) Children and guardians have good compliance

Exclusion criteria

Exclusion criteria: (1) Eye or systemic diseases are not suitable for wearing orthokeratology glasses; (2) Those allergic to atropine; (3) It is necessary to use treatment programs that affect the degree of myopia (such as hormones, etc.); (4) poor personal hygiene habits, poor compliance, can not cooperate with the examination, timely treatment and regular review of the hospital; (5) Other circumstances that the investigator determines may affect the conduct of the clinical study and the results of your study are not suitable for inclusion in the study

Design outcomes

Primary

MeasureTime frame
diopter;axial length;visual function;

Secondary

MeasureTime frame
corneal topographic map;best corrected visual acuity;intraocular pressure;anterior segment;Degree of phoria;choroidal thickness;pupil size;Schirmer test;breakup time of tear film;

Countries

China

Contacts

Public ContactYuelan Feng

The First Affiliated Hospital of Baotou Medical College

fyl-2006-ky@163.com+86 150 4497 3994

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026