Membranous nephropathy
Conditions
Interventions
Without early segmental lesions and FSGS lesions (FSL -):N/A
With early segmental lesions (EFSL+):N/A
With FSGS lesions (FSGS+):N/A
Sponsors
The People’s Hospital of Guangxi Zhuang Autonomous Region
Eligibility
Sex/Gender
All
Age
16 Years to 85 Years
Inclusion criteria
Inclusion criteria: Primary membranous nephropathy, with a follow-up period of no less than 6 months. 40 cases were included in the group with early segmental lesions (EFSL+), 40 cases with FSGS lesions (FSGS+), and 40 cases without early segmental lesions and FSGS lesions (FSL -). Select normal kidney tissue around the pathological kidney tumor resection specimen that is relatively unaffected as a control.
Exclusion criteria
Exclusion criteria: Exclude patients with secondary glomerular membrane diseases such as HBV, HCV related, autoimmune diseases, tumors, drugs, and also exclude patients with non virus related membrane nephropathy and diabetes associated with HBV and HCV viruses. Exclude patients with less than 8 intact glomeruli in pathological sections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decline of baseline GFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical remission;Complications such as infection;End stage renal disease, ESRD; | — |
Countries
China
Contacts
Public ContactHongguang He
The People’s Hospital of Guangxi Zhuang Autonomous Region
Outcome results
None listed