Gynecological diseases
Conditions
Interventions
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: a) Elective gynecological laparoscopy surgery under general anesthesia is planned b) ASA ? ~ II c) Patients are conscious and actively cooperated with the study d) Agree to participate in the clinical trial and sign the informed consent voluntarily e) Age 18-65 years old f) No abnormality in blood coagulation, blood routine, biochemical examination and electrocardiogram before operation g) Body mass index (BMI) 18–28kg/m^2
Exclusion criteria
Exclusion criteria: a) Allergic to esketamine b) Severe cardiac or pulmonary dysfunction c) Severe hepatic or renal dysfunction d) Severe risk of elevated blood pressure or intracranial pressure e) Patients with poorly controlled or untreated hypertension (arterial hypertension, resting systolic/diastolic blood pressure over 180/100 MMHG); f) Patients with untreated or undertreated hyperthyroidism (hyperthyroidism) g) Long-term use of sedative analgesics h) Patients who have a history of mental illness I) Participated in a clinical trial for nearly three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scores on SAS and SDS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery 40 scores;ISI scores;VAS Scores;hemodynamics;Adverse reactions; | — |
Countries
China
Contacts
Public ContactLin Li
General Hospital of Northern Theater Command
Outcome results
None listed