Periodontal disease
Conditions
Interventions
Geistlich Mucograft Group:Mucograft collagen membrane material passed clinical safety test was used
iRegen Group:iRegen collagen membrane material passed clinical safety test was used
Sponsors
PLA Air Force Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 50 Years
Inclusion criteria
Inclusion criteria: ? Patients are aged between 25 and 50 years old ? The width of attached gingival retraction is greater than or equal to 2 mm ? No obvious malocclusion ? Patients who can maintain good oral hygiene (5) No systemic diseases affecting the course of periodontal disease ? No abnormal attachment was found in the frenulum ? No periodontal operation within 12 months
Exclusion criteria
Exclusion criteria: Those who have one of the following circumstances should be excluded and cannot be included: ? The root surface of the tooth can not obtain normal attachment ? Root caries that need to be repaired ? Heavy smokers (> 10 sticks per day) (4) Systemic diseases affecting the course of periodontal disease [such as diabetes, hypertension, radiotherapy history or cancer treatment history, such as liver, kidney, hematopoietic system and other serious primary diseases, or liver function abnormalities, AST, ALT greater than 1.1/2 times the normal value, creatinine greater than the upper limit of normal value; psychiatric patients; tumor patients, expected life < 6 months; Patients with renal insufficiency (creatinine, urea nitrogen more than 1.2 times the normal range) with a history of immunodeficiency, including HIV positive or other acquired, congenital immunodeficiency diseases, or a history of organ transplantation] (5) Allergic to anesthetics and other drugs ? Pregnant or lactating women ? Refused to participate in this clinical researcher for various reasons ? Partners or first-degree relatives of research center staff or researchers ? Other situations in which the researchers considered unsuitable for inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Buccal attached gingival width;Buccal attached gingival thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Attached gum color;Attached gingival edema;Patient's pain; | — |
Countries
China
Contacts
Public ContactXinyue Xu
PLA Air Force Military Medical University
Outcome results
None listed