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Dose-response effect of tai chi combined with transcranial direct current stimulation on mild cognitive impairment

Dose-response effect of tai chi combined with transcranial direct current stimulation on mild cognitive impairment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075816
Enrollment
Unknown
Registered
2023-09-15
Start date
2023-10-01
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Taichi+0mA tDCS:Taichi+0mA tDCS
Taichi+1mA tDCS:Taichi+1mA tDCS
Taichi+2mA tDCS:Taichi+2mA tDCS

Sponsors

College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of MCI; 2. The score of Montreal Cognitive Assessment scale(MoCA) higher than 18 and lower than 26, and if the years of education were less than 12 years, the score should be added 1 score; 3. The score of Activity of Daily Living Scale(ADL) less than 22; 4. Meet the level of global deteriorate scale 2-3; 5. Aged 50 to 75 years; 6. Not engaged in regular exercise in the last six months (regular exercise means exercise with a frequency of at least three times a week and at least 20 min per session); 7. No contraindications of tDCS; 8. The Participants had informed consent and participated voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients with cognitive impairment caused by depression,the depression patients with score of GDS-15 more than or equal 9; 2. Patients with cognitive impairment caused by taking drugs (antipsychotics; benzodiazepines, etc.), poisoning and other reasons; 3. Patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100 mmHg after medication); 4. Participants cannot cooperate to complete the exercise program, such as motor dysfunction caused by nervous system diseases (stroke, Parkinson's disease), musculoskeletal system diseases (lower limb arthritis, history of hip and knee replacement, etc.), serious organ diseases and other exercise contraindications; 5. Participants cannot complete the index evaluation, such as severe aphasia, audio-visual impairment, illiteracy, etc; 6. Participants in other research trials that are participating in and influencing the results of this study; 7. Taking any medications in the past 6 months which may cause impaired or improved cognitive performance.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment;The Chinese version of the Wechsler Memory Scale for adults;

Secondary

MeasureTime frame
Auditory verbal learning test;The Rey-Osterrieth complex figure test (ROCF);N-Back working memory test;

Countries

China

Contacts

Public ContactXuying

College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine

aaa8858@qq.com+86 137 9932 6706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026