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Effectiveness of Integrative Mindsight Therapy in anxiety, depression and quality of life in nasopharyngeal carcinoma who receive radiotherapy: A randomized controlled pilot study

Effectiveness of Integrative Mindsight Therapy in anxiety, depression and quality of life in nasopharyngeal carcinoma who receive radiotherapy: A randomized controlled pilot study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075801
Enrollment
Unknown
Registered
2023-09-15
Start date
2023-09-18
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasopharyngeal carcinoma

Interventions

Integrative Mindsight Therapy group:Integrative Mindsight Therapy is a cognitive behavioral psychotherapy based on mindfulness intervention and integrated with clinical oncology. It is an integrated m
Health education group:Patients will receive routine care and health education. We would provide knowledge about nasopharyngeal carcinoma and radiotherapy, such as pathogenesis of nasopharyngeal carci

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients who have been newly diagnosed with nasopharyngeal carcinoma (within the previous month), whose diagnosis has been confirmed by a histopathological examination report 2.Patients aged 18 - 65 years old. 3.Patients with education that is junior high school or above. 4.Patients who plan to receive the standard regime of radiotherapy with or without chemotherapy. 5.Patients who have developed depression and anxiety symptoms after their head and neck cancer diagnosis with a"Hospital Anxiety and Depression Scale" (HADS) depression subscale score of = 8 and anxiety subscale score of = 8.

Exclusion criteria

Exclusion criteria: 1.Have a history of pre-existing psychiatric illness. 2.Patients with suicidal tendencies. 3.Patients with metastasis to the central nervous system. 4.Patients currently receive any psychotherapy or counseling. 5.Patients are physically unfit for this study’s interventions (for example those who are bed-bound or too weak to engage in the study interventions, KPS=60). 6.Exhibit cognitive impairment (patients will be screened via conversion with doctors) 7.Patients who are unable to read and understand written mandarin 8.Patients who refuse to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
The anxiety and depression levels of patients three months after intervention;

Secondary

MeasureTime frame
The anxiety and depression levels of patients afer four IMT, the end of intervention, 6 m and 12 m;The changes of quality of life;The changes of Cancer related fatigue;The changes of total psychologic health;The changes of quality of sleep;The compliance of radiotherapy and chemotherapy;Immune function of patients;Overall survival;Progression free survival;

Countries

China

Contacts

Public ContactYong Chen

The First Affiliated Hospital of Sun Yat-sen University

chenyong@mail.sysu.edu.cn+86 138 2626 6676

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026