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Clinical application of platelet-rich plasma combined with Nd:YAG laser in the treatment of erosive oral lichen planus

Clinical application of platelet-rich plasma combined with Nd:YAG laser in the treatment of erosive oral lichen planus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075800
Enrollment
Unknown
Registered
2023-09-15
Start date
2023-09-15
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erosive oral lichen planus

Interventions

Study Group :The study group (40 cases), patients were treated with autologous platelet-rich plasma gel topical application at the same time as Nd:YAG laser treatment once a week for 8 weeks
Control Group:The control group (40 cases) were treated with Nd:YAG laser for 8 weeks.

Sponsors

Xuzhou Central Hospital, Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with keen perception and no contraindications to laser therapy; (2) Patients who have not received other analgesic or antibiotic drugs at the lesions; (3) Intraoral lesions of the same type; (4) Patients who are willing to receive laser therapy (5) Patients who receive autologous blood therapy.

Exclusion criteria

Exclusion criteria: (1) patients with lichenoid changes of the oral mucosa; (2) patients with serious systemic diseases; (3) other oral mucosal diseases; (4) pregnant/lactating women; (5) patients who have taken other analgesic drugs; (6) patients with poor follow-up and cannot be seen on time; (7) patients with blood system diseases and anemia; (8) allergic to coagulation drugs.

Design outcomes

Primary

MeasureTime frame
Efficacy indicators;VAS score Pain indicators;

Countries

China

Contacts

Public ContactZheng Hao

Xuzhou Central Hospital, Jiangsu Province

kupffer@163.com+86 189 5226 0995

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026