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The Impact of Clearing Pharyngeal Secretions on Pain-Free Gastroscopy in Smokers: A Prospective, Randomized, Case-Control Study

The Impact of Clearing Pharyngeal Secretions on Pain-Free Gastroscopy in Smokers: A Prospective, Randomized, Case-Control Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075785
Enrollment
Unknown
Registered
2023-09-15
Start date
2023-09-15
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper gastrointestinal disease

Interventions

Experimental group:oropharyngeal secretions clearance performed by professional non-blinded researchers
control group:no oropharyngeal secretions clearance performed

Sponsors

Xiangya Third Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age between 18 and 75 years, regardless of gender. 2.Smoking history of at least 5 years, with a daily cigarette consumption of at least 10 cigarettes. Planned to undergo pain-free gastroscopy under general anesthesia. No severe cardiac, hepatic, or renal dysfunction. No history of allergies. Voluntary participation in the study and signing an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Pregnant women. 2.Severe cardiovascular or pulmonary diseases. 3.Acute respiratory tract infection. 4.History of oropharyngeal surgery. 5.Conditions such as hiatal hernia, tracheoesophageal fistula, esophageal fistula, gastroesophageal reflux, or achalasia. 6.Snoring. 7.Asthma. 8.Other conditions deemed unsuitable for inclusion by the researcher's judgment.

Design outcomes

Primary

MeasureTime frame
Occurrence of cough reflex; occurrence of vomiting reflex;occurrence of hypoxemia;occurrence of laryngospasm;administration of oxygen via face mask;

Secondary

MeasureTime frame
presence of secretions;occurrence of assisted respiration;procedure time;recovery time;operator satisfaction rating;patient satisfaction rating;

Countries

China

Contacts

Public ContactLi Gong

The Third Xiangya Hospital of Central South University

ligong@csu.edu.cn+86 134 6751 1233

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026