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Perioperative Analgesic Effects of Esketamine or Oxycodone or Sufentanil for Laparoscopic Cholecystectomy: A Prospective, Randomized, Clinical Trial

Perioperative Analgesic Effects of Esketamine or Oxycodone or Sufentanil for Laparoscopic Cholecystectomy: A Prospective, Randomized, Clinical Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075752
Enrollment
Unknown
Registered
2023-09-14
Start date
2023-09-15
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gallbladder and biliary diseases.

Interventions

Sponsors

Funing People's Hospital of Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All the patients included in this review underwent elective laparoscopic cholecystectomy. 1.male and female patients between 18 and 65 years of age; 2.American Society of Anesthesiology (ASA) score of I or II ; 3.body mass index (BMI) of 18–30 kg/m2;

Exclusion criteria

Exclusion criteria: 1.unplanned emergency surgery; 2.severe cardiac insufficiency(EF < 30%) or serious lung diseases( type I or II respiratory failure); 3.mental illness or diminished cognitive function, or taking long-term antipsychoticor related drugs, or drug users; 4.allergies or contraindications to any of the study drugs; 5.Patients who had contraindications to nerve block, and can-not tolerate a phrenic nerve block. 6. long-standing pain or neuropathic pain; 7.gallstones with gallbladder perforation, diffuse peritonitis or acute pyogenic cholangitis; 8.illiterate, or understand the study scoring.

Design outcomes

Primary

MeasureTime frame
Pain conditions, including incision pain, visceral pain and referred pain (shoulder pain).;

Secondary

MeasureTime frame
General characteristics of the patients,Demographic and clinical characteristics ;the perioperative conditions ;Postoperative Situation and the wake-up period conditions ;adverse reactions;

Countries

China

Contacts

Public ContactDekun Yin

Funing People's Hospital of Jiangsu Province

153761717@qq.com+86 158 0511 0243

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026