Postoperative Pulmonary Complications
Conditions
Interventions
Dexmedetomidine Group(DEX):Intravenous dexmedetomidine infusion
Control Group(C):Intravenous physiological saline infusion
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1: The patient is older than or equal to 65 years old 2: Proposed laparoscopic gastrointestinal surgery 3: American Society of Anesthesiologists physical status ?~?
Exclusion criteria
Exclusion criteria: 1: Dexmedetomidine allergy or contraindication 2: Suffer from other serious systemic disease (serious heart, kidney, or liver and lung disease) 3: Drug and alcohol addiction and mental disorders 4: BMI>30kg/m² 5: Expected to be transferred to ICU after surgery 6: The operation is expected to less than two hours 7: A history of upper respiratory or lung infection in the past 4 weeks 8: There was severe pleural effusion and atelectasis before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Postoperative Pulmonary Complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Surfactant Related Protein-D (SP-D);IL-6;TNF-a;Blood Gas Analysis; | — |
Countries
China
Contacts
Public ContactSun Defeng
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed