Endometriosis
Conditions
Interventions
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: (1)Signed informed consent form. (Specific grouping according to patient's wishes) (2) Aged 20-35 years with fertility requirements (3) Meet the clinical diagnostic criteria for endometriosis ( Guidelines for the management of endometriosis (3rd edition)) (4) Typical ultrasonographic (transrectal/transabdominal/transvaginal) presentation of an ovarian endometriosis cyst ( Guidelines for the Management of Endometriosis (3rd edition)) (5) Maximum diameter of single-compartment cysts / total diameter of multi-compartment cysts of 4-6 cm (6) Patients with primary treatment of endometriosis
Exclusion criteria
Exclusion criteria: (1) Patients involved in other interventional research projects. (2) Patients with poor living status, incapacity or unable to follow up for long periods of time. (3) Patients with other co-morbidities that reduce fertility (e.g. genital tract abnormalities, premature ovarian failure, PCOS, etc.) (4) Patients with a history of previous ovarian surgery or other causes of pelvic pain. (5) Excessive rise in CA125 within a short period of time or rapid cyst enlargement of a nature not excluding malignancy. (6) Receiving hormonal preparations containing progestins, oestrogens, gonadotropin-releasing hormone analogues, testosterone derivatives, oestrogen antagonists, aromatase inhibitors and other drugs or their derivatives that are thought to affect sex hormone secretion within 3 months. (7) Pregnant or lactating women. (8) Presence of abnormal vaginal bleeding of undetermined origin. (9) Patients with any disease or condition that may worsen under hormonal therapy. (10) Hypersensitivity to any component of the drug to be administered. (11) Ultrasound or MRI suggestive of combined adenomyosis (12) Other indications for surgical treatment of endometriosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian reserve function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health-related quality of life;The relief of pain associated with endometriosis;Size of endometrioma;The patient's overall impression of the treatment effect;Proportion of patients who require medication after surgery;The direct economic costs of different treatments; | — |
Countries
China
Contacts
Public ContactYi Dai
Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences
Outcome results
None listed