epilepsy
Conditions
Interventions
Experimental group:Individualized closed-loop stimulation
Sponsors
Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) 2-18 years old, regardless of gender; (2) patients diagnosed with medically intractable epilepsy and need to undergo surgical treatment; (3) The stereotactic intracranial electrode has been implanted in patients, patients have been monitored for 3-5 times or more epileptic seizures, the focal epilepsy has been diagnosed, and functional mapping was completed; (4) Patients or their family members can fully understand the treatment, have good compliance, can cooperate with researchers to complete the whole clinical study, and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients diagnosed with epilepsy combined with epileptic pseudoseizures; (2) Patients complicated with severe mental or nervous system diseases; (3) Coagulation dysfunction and inability to stop anticoagulant drugs; (4) Neurosurgical contraindications; (5) Unable to comply with the protocol to complete the study or/and follow-up; (6) Patients who are participating in other clinical trials and have not yet been out of group; (7) Other conditions considered inappropriate for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse event rate;epileptic seizure detection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| the percentage reduction of timing of seizure;Fall-out ratio; | — |
Countries
China
Contacts
Public ContactLiang Shuli
Beijing Children's Hospital, Capital Medical University
Outcome results
None listed