coronary heart disease
Conditions
Interventions
Experimental group:The combination of traditional Chinese and Western medicine with cardiac rehabilitation program was adopted for 3 months, and the control group was treated with ginseng decoction.
Control group:Standard Western cardiac rehabilitation protocol was adopted for 3 months.
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-85 years old, gender unlimited. (2) In the second stage of coronary heart disease cardiac rehabilitation. (4) The risk of coronary heart disease was divided into medium and low risk. (5) TCM syndrome differentiation is deficiency cold type. (6) Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Combined with rheumatic heart disease, pulmonary heart disease, hypertrophic cardiomyopathy, severe valvular disease, acute myocarditis, acute pericarditis, aneurysm (dissection) and other cardiovascular diseases. Gastroenteritis, gastrointestinal ulcers, cirrhosis of the liver, chronic kidney failure, and other problems affecting the gut microbiota. (2) Uncontrolled metabolic diseases, such as hyperthyroidism and myxedema; Acute infection, malignant tumor, blood disease, thrombotic disease and other non-cardiac diseases. (3) Pregnant or lactating women. (4) physical disability or dysfunction; Mental disorders can't work together. (5) Antibiotics or probiotics have been used within 2 months before the collection of stool samples. (6) Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment efficiency and TCM syndrome score;Cardiopulmonary exercise test;Tumor necrosis factor alpha;Interleukin-6;hs-CRP;mRNA levels of TLR-4/NF-?B;TMAO;Intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ox-LDL;TC;LDL-c;HDL-C;TG; | — |
Countries
China
Contacts
Public ContactChen Qiaofeng
Wuxi Mental Health Center
Outcome results
None listed