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Characterization of distinct peripheral blood immune cell subsets and identification of molecular markers in asthma patients

Characterization of distinct peripheral blood immune cell subsets and identification of molecular markers in asthma patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075710
Enrollment
Unknown
Registered
2023-09-13
Start date
2023-09-15
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial Asthma

Interventions

Sponsors

Shanghai Research Institute of Acupuncture and Meridian
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: For bronchial asthma: 1. Age ranged from 18-65 years old without gender limitation; 2. Patients diagnosed with bronchial asthma according to the "2016 guidelines for the prevention and treatment of bronchial asthma of the Chinese respiratory society" and the "2019GINA". 3. Patients who voluntarily participate in the study and sign the informed consent. For health control: 1. Age ranged from 18-65 years old without gender limitation; 2. Patients diagnosed with no bronchial asthma according to the "2016 guidelines for the prevention and treatment of bronchial asthma of the Chinese respiratory society" and the "2019GINA". 3. Patients who voluntarily participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: For bronchial asthma: 1) Have participated in or are currently participating in other clinical trials within 1 month prior to this study; 2) Use of systemic glucocorticoids within 1 month prior to the study; 3) Systemic infection or respiratory bacterial infection, tuberculosis, fungal infection within 1 month prior to the study; 4) Severe acute asthma attack and hospitalization within the past 3 months prior to the study; 5) Changes in regular asthma treatment during the initial 3 months of the study period; 6) Patients with significant underlying conditions such as hypertension, tumor, cardiovascular disease, liver disease, kidney disease, and hematopoietic disorders; 7) Asthma caused by other diseases such as tuberculosis, bronchiectasis, and cardiac insufficiency; 8) Hyperthyroidism diagnosis; 9) Presence of mental illnesses that impair self-control and accurate expression; 10) Pregnant or lactating women; 11) Other conditions deemed unsuitable for participation in the study by healthcare professionals. The patient's apparent illness raised concerns among researchers regarding potential risks or impact on study results. For health control: 1) Have participated in or are currently participating in other clinical trials within 1 month prior to this study; 2) Use of systemic glucocorticoids within 1 month prior to the study; 3) Systemic infection or respiratory bacterial infection, tuberculosis, fungal infection within 1 month prior to the study; 4) Patients with other allergic conditions, such as allergic rhinitis and allergic dermatitis. 5) Patients with significant underlying conditions such as hypertension, tumor, cardiovascular disease, liver disease, kidney disease, and hematopoietic disorders; 6) Hyperthyroidism diagnosis; 7) Presence of mental illnesses that impair self-control and accurate expression; 8) Pregnant or lactating women; 9) Other conditions deemed unsuitable for participation in the study by healthcare professionals. The patient's apparent illness raised concerns among researchers regarding potential risks or impact on study results.

Design outcomes

Primary

MeasureTime frame
lung function;Quality of Life Score;Peripheral blood eosinophil count;Peripheral blood inflammatory cytokines;

Secondary

MeasureTime frame
General clinical data;

Countries

China

Contacts

Public ContactChen Yanjiao

Shanghai Research Institute of Acupuncture and Meridian,Yueyang Hospital of Integrated Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine

cyjb1018@163.com+86 131 6250 7559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026