fluorosisofbone
Conditions
Interventions
Ginkgo biloba & Epimedium groups:Ginkgo biloba and Epimedium three times a day for three months.
Xianlingbao & Cortex Eucommia groups:Xianlingba and Cortex Eucommia three times a day for three months.
Osteoporosis & Prickly Pear Groups:Osteoporosis and Prickly Pear three times a day for three months.
Sponsors
Guizhou Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Residents aged 40~years old, with the same place of residence and place of origin; 2. Voluntarily participating in the project, agreeing to collect biological samples and signing an informed consent form; 3. Free of mental and other related diseases, with normal expression and comprehension; 4. Combined with the diagnostic standard of endemic fluorosis in WS/T 192-2021, the patients can be diagnosed as patients with endemic fluorosis.
Exclusion criteria
Exclusion criteria: 1. Those who have received interventions and treatments with other drugs related to the treatment of fluorosis in the country; 2. Those who have abnormalities in liver and kidney functions in routine blood tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| X-ray Signs of Fluorosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical Functioning;Bodily Pain;Mini-mental State Examination,MMSE;Assessment of Joint Mobility Measurement; | — |
Countries
China
Contacts
Public ContactLUO PENG
Guizhou Medical University
Outcome results
None listed