Type 2 diabetes
Conditions
Interventions
CGM:Real-time dynamic blood glucose monitoring
Control:self monitoring of blood glucose
Sponsors
Department of Endocrinology, Peking University First Hospital
Eligibility
Sex/Gender
All
Age
17 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Diagnosed type 2 diabetes 2) Joined the "diabetes Joint Care Clinic of Peking University First Hospital" for more than 12 months 3) Glycated hemoglobin = 9% measured at baseline, or Glycated hemoglobin = 7% when joining the nursing clinic, and Glycated hemoglobin>7% after 24 weeks of follow-up. HbA1c testing is a centralized test or has passed the national GHbA1c standardized laboratory test results. 4) 18-70 years old (including), with a body mass index (BMI) of 20-35kg/m2; 5) Have not used real-time dynamic blood glucose monitoring equipment; 6) Stable treatment with hypoglycemic drugs for at least 3 months 7) Able and willing to use continuous glucose monitoring and blood glucose monitoring in accordance with project requirements, and accept management of healthy lifestyle outside the hospital; 8) Volunteer to participate in this study and sign an informed consent form
Exclusion criteria
Exclusion criteria: 1) Diagnosis of non type 2 diabetes; 2) There are acute complications of diabetes (including Diabetic ketoacidosis, hyperglycemia and hyperosmolality, Lactic acidosis) 3) Severe microvascular complications: proliferative retinopathy; Urinary albumin/creatinine>300mg/g, or 24-hour urine protein quantification>1g/d; Uncontrolled painful diabetes neuropathy and significant diabetes autonomic neuropathy; 4) Significant complications of Great vessels: those who have had acute cerebrovascular accident, acute coronary syndrome, peripheral artery disease requiring hospitalization for vascular intervention or amputation within 3 months before enrollment; 5) Blood pressure continuously exceeds 180/110 mmHg and cannot be controlled within 160/110 mmHg within one week; 6) The clearance rate of blood creatinine is less than 30ml/min/1.73m2 (calculated according to the CKDEPI formula), alanine aminotransferase is = 3 times the upper limit of normal, and total bilirubin is = 2 times the upper limit of normal and lasts for more than 1 week; 7) Hemoglobin<100g/L or requiring regular blood transfusion treatment; 8) Drugs that may affect blood glucose have been used for more than one week accumulatively within 12 weeks, such as oral/intravenous glucocorticoid, growth hormone, estrogen/Progestogen, high-dose Diuretic, antipsychotic drugs, etc; However, small doses of Diuretic (Hydrochlorothiazide<25mg/d, Indapamide = 1.5mg/d) for the purpose of lowering blood pressure, as well as the physiological amount of Thyroid hormones for alternative treatment, are not limited; 9) Systemic infection or severe accompanying diseases; Patients with malignant tumors or chronic diarrhea; 10) Known (or suspected) severe allergy to medical grade adhesives 11) Mental or Communication disorder; 12) Chronic heart failure, with a heart function grading of III or above; 13) Pregnant, breastfeeding, women of childbearing age who are unwilling to use contraception during the study period, or have surgery plans that require general anesthesia in the near future (within 6 months); 14) The subject is uncooperative, unable to follow up, or the researcher determines that it may be difficult to complete the study. 15) Other situations that the researcher determines are not suitable for inclusion. The research doctor will determine whether you are suitable to participate in this study based on your actual situation and the inclusion and exclusion criteria in the research protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c;Self management ability rating; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time in rage;Time above rage;Time below rage;MARD;HbA1c decrease percentage = 0.5%;APP online time;Nurse intervention time;Percentage of new or reduced diabetes drugs;HOMA-IR;C-peptide;Diabetes Self-CareScale;SF-36 Scale; | — |
Countries
China
Contacts
Public ContactGu Nan
Peking University First Hospital
Outcome results
None listed