Diseases of limbs or lower abdomen requiring surgery
Conditions
Interventions
A group:Firstly, data on the plane of anesthesia are obtained by patient self-report using intermittent mechanical stimulation with von-Frey filaments in the awake state. Then data on the plane of ane
B group:Firstly, data on the plane of anesthesia are obtained by the NOX index using intermittent mechanical stimulation with von-Frey filaments in the propofol-anesthetized state. Then data on the pl
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years old; 2. Elective surgery to receive spinal anesthesia or brachial plexus block; 3. ASA class I-III; 4. BMI 18-28 kg/m2; 5. Volunteer to participate in this study and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe hepatic or renal dysfunction, or abnormal coagulation; 2. Central nervous system diseases such as intracranial hypertension; 3. Psychiatric diseases such as schizophrenia, mania or insanity; 4. Puncture site or systemic infection, etc; 5. Inability to cooperate during puncture, affecting the operation of puncture; 6. Long-term use of sedative or analgesic drugs 7. Those who are allergic or contraindicated to local anesthetics, fentanyl, propofol, lipid emulsions and benzodiazepines and their components; 8. Patients who are unable to accurately express the range and degree of pain; 9. Other conditions judged by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plane of anesthesia for regional block; | — |
Secondary
| Measure | Time frame |
|---|---|
| BISpro index;NOX index;VAS pain scores;Mean arterial pressure;Heart rate; | — |
Countries
China
Contacts
Public ContactLiao Qin
The Third Xiangya Hospital of Central South University
Outcome results
None listed